971 Oral vitamin D3 as mitigator of chemical-induced skin inflammation
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چکیده
منابع مشابه
Vitamin D3 intoxication induced secondary Hypertension
Background: The effects of vitamin D in skeletal system, biological metabolism and immune system function are well shown. Cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are two major types of vitamin D. Vitamin D deficiency is widely in human population and vitamin D intoxication is very rare. Case Description: The patient is 37-years old bodybuilder man who referred to emergency...
متن کاملActive Vitamin D3 Ointments Suppress Ultraviolet B Irradiation-Induced Papilloma Formation in Mouse Skin
Background: Topical application of 1a, 25-dihydroxyvitamin D3 (1-a,25-(OH)2D3) inhibits7, 12-dimethylbenz [a] anthracene (DMBA) and 12-a-tetradecanoylphorbol-13-acetate (TPA)-induced tumor formation of mouse skin. Ultraviolet irradiation (UV) may also induce skin tumors. However, no report exists regarding the effect of topical active vitamin D3, tacrolimus, or corticosteroids on UV-irradiation...
متن کاملOral vitamin D3 decreases fracture risk in the elderly.
Vitamin D3 (or its physiologic equivalent, ergocalciferol), administered at a dose of 100,000 IU every 4 months for 5 years, is effective for primary prevention of fractures in the active elderly aged 65 to 85 years. This treatment regimen has no effect on cardiovascular, cancer, or all-cause mortality. Despite a seemingly large dose averaging 800 IU per day, this regimen is a safe, cheap (<$2 ...
متن کاملDietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D3 metabolism
RATIONALE Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency on inflammation and VD3 metabolism in an Aspergillus fumigatus (Af) mouse model of chronic rhinosi...
متن کاملVitamin D3 influence the Th1/Th2 ratio in C57BL/6 induced model of experimental autoimmune encephalomyelitis
Objective(s): Multiple Sclerosis (MS) is known as a progressive inflammatory CNS disease. Cytokines belong to Th1 or Th2 family and inflammatory cells, play significant role in pathophysiology of MS. Thus, any treatment supposed to influence the relation between Th1 to Th2 cytokines expression. Although vitamin D has been prescribed as a therapeutic supplement of MS for a long time, it is not c...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.1047